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　　本作将聚焦于反毒战争的起源 – 墨西哥的瓜达拉哈拉贩毒集团，时间也将移前至80年代，讲述冷静﹑大胆﹑头脑清晰﹑忠于 亲友的Felix Gallardo（Diego Luna饰）如何把散乱的贩毒者统一起来，成为被称为「Godfather」的大毒枭。Supplier unit or agency:《紧急救命》里的菜鸟实习医生们，不再是刚来时手忙脚乱的样子，各人都有了不小的成长和变化，也加深了困惑。蓝泽（山下智久 饰）纠结于家庭；白石（新垣结衣 饰）看似变得自信，实则仍对牵连黑田医生（柳叶敏郎 饰）一事感到愧疚；绯山（户田惠梨香 饰）因为之前救援意外受伤而留下了伤疤，害怕手术；滕川（前利阳介 饰）依然是他们几个当中最一般的人；而护士冴岛（比嘉爱末 饰）则和患病的男友面对生死离别。医院方面取代黑田的是新调来的医生桔启辅（椎名桔平 饰），和黑田的风格完全不同。新的挑战接踵而来，是去是留依然是个未知数。于洪天和杜健康来到健康制药，却发现资料已经被删除。正在杜健康重建文档的时候，整栋大楼的电源被邓斌切断。于洪天带着杜健康逃出大楼，躲进地下停车场。于洪天教杜健康怎样用枪，两人决定并肩奋战，直到耿鹃带人支援。在与邓斌的激战中，杜健康为了掩护于洪天被子弹打中。最终黑虎将邓斌抓住。邓斌供认说自己就是天堂鸟。专案组经过讨论认为邓斌应该不是天堂鸟，他身后应该还有更大的敌人陈启不紧不慢的说着，声音回荡在偌大的房间中。《毒枭》在经过三季于哥伦比亚的反毒战争后将告一段落。Netflix将原来的第四季独立出来作为衍生剧《毒枭：墨西哥篇》（Narcos: Mexico）。Tang Lin, producer of CCTV's financial channel "Charming China City", Reveals Innovative Highlights of the Second Season's Purpose: First, the timing of the second season of the program is better than that of the first season. The 19th National Congress and the National Two Sessions have been held one after another. At the same time, the 40th anniversary of reform and opening-up is a great moment. From the perspective of the country, we can see the pace of our city and the pace of China. Second, humanistic care is more intense. We only do two rounds of competition, so that the city can focus on the program and carry out intensive cultivation, so that the charm of the city can be better released. Third, we should use real elements to express our love for the city. We will follow the process of filming all the city competitions and rehearsals, and aspire to set up a biography for each city. Competition is only a means, reality is the end.